Mps1 for anticancer therapy.

This is a Combo Order: Please add PYMOL software The research will be focused on inhibition of Mps1 for anticancer therapy and protein drug interaction. use subheading in introduction, method, results and discussion section. computational work add to the project to look at the 3D structure of Mps1 kinase in complex with inhibitors. By using pymol Mps1 kinase complex inhibitors structures P (20-40) at least using data analysis for the results of comparing the structures, features. For the result section use PDA codes for the table with DPA names and a drawn inhibitor. Mps1 mutations that are associated with cancer and the small size inhibitors of this protein kinase that have been reported to date. The aim will be to compare the efficacy of the various types of drugs (ATP-analogues) with the specific tumour type(s) the drugs are effective against. This is important to correlate the chemical features of the inhibitors with the Mps1 mutations that are associated with cancer (eg, not all the Mps1 kinase inhibitors have the same effect on different cancer tissues)